【アステラス製薬株式会社】Scientist I, T cell ＆ Immune Modulation Biology

【About Astellas】　 Astellas is a global life sciences company committed to turning innovative science into VALUE for patients. We provide transformative therapies in disease areas that include oncology, ophthalmology, urology, immunology and women's health. Through our research and development programs, we are pioneering new healthcare solutions for diseases with high unmet medical need. Are you driven to make a real difference in the lives of patients? We're seeking passionate individuals who thrive in dynamic environments, embrace new ideas, and aren't afraid to take intelligent risks. People who act with unwavering integrity and are deeply committed to making a tangible impact. 【募集の背景 / Purpose & Scope】 This is a pharmacologist position developing antibody therapeutics, such as T cell engager, for treating cancer based on the deeper biological understanding of modulating T cell activation. The position holder will have responsibility of own pharmacology studies, drive pharmacological study and report to pharmacology lead and Research Lead in each project. The pharmacological study includes in vitro and in vivo preclinical study to evaluate anti-tumor activities and MOA analysis of drug candidates for IND submission. 【職務の内容 / Essential Job Responsibilities】 （雇入れ直後） 1. Plan and conduct appropriate non-clinical pharmacological studies, including animal studies, necessary to advance oncology projects, such as target identification, selection of drug candidates, confirmation of MOA, estimation of human dose, and exploration of combination drugs, under the guidance of the manager and team leader. 2. Work in a team-oriented laboratory environment under the guidance of the manager and team leader, within cross-functional research teams (product creation, pharmacokinetics, safety, CMC, etc.) and other internal/external collaborators/stakeholders. 3. Prepare patent specifications for parts related to non-clinical pharmacology data for patent filing of drug candidates. 4. Provide leadership, mentorship, and scientific/technical guidance to junior staff as opportunities arise. （変更の範囲） 会社内での全ての業務

・This position is based in Tsukuba Research Center and will require on-site work. 【勤務地 / Location】 （雇入れ直後） 茨城県つくば市　アステラス製薬　つくば研究センター Tsukuba, Ibaraki ※ＪＲひたち野うしく駅とつくばエクスプレス（TX)　研究学園駅より通勤バスがございます。 （変更の範囲） 会社の定める事業場および自宅 【勤務開始日 / Start Date】 応相談 Will be decided according to the candidate's flexibility 【契約期間 / Contract Duration】 期間の定めなし Not limited to specified period 【試用期間 / Probation Period】 試用期間原則なし No probation period in principle 【給与 / Salary】 ①基本給：当人の経歴・技術・技能等を考慮して決定 ②フレックスタイム制の場合：月間の所定労働時間を超えて勤務する時間に対して時間外勤務手当を支給 ①Base salary: will be decided by the candidate's experience, skill and capability. ②When Flextime System is applied: Overtime allowance will be paid for time worked in excess of prescribed working hours. 【昇給 / Salary Raise】 有り 【賞与 / Bonus】 有り 【諸手当 / Allowance】 裁量労働手当、住宅手当、通勤手当　等 Discretionary work allowance, Housing allowance, Commutation allowance, etc. 【勤務時間 / Working Hours】 8:00～17:00（月～木）、8:00～15:15（金）、スーパーフレックス制 8:00～17:00（Mon～Thu）、8:00～15:15（Fri） Flex-time system or Discretionary Work System 【休日 / Holidays】 完全週休２日制（土曜・日曜）、祝日、5月1日、夏季、年末年始 Weekends(Sat and Sun), holidays, May 1st, summer vacation, New Year holidays 【休暇 / Vacation Leave】 年次有給休暇、育児休業制度、介護休業制度　等 Annual paid leave, childcare leave system, nursing care leave system, etc. 【福利厚生 / Welfare】 雇用保険、労災保険、厚生年金、健康保険、共済会制度、社宅制度、持株会制度、財形貯蓄制度　等 Employment Insurance, Industrial Accident Compensation Insurance, Welfare Pension Insurance, Health Insurance, Mutual Aid Association System, Company Housing System, Employee Shareholder Association System, Property Accumulation Savings System