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Senior Scientist, Molecular Pathology Group【100年以上の歴史を持つ日系製薬メーカー】

年収:800万 ~ 1100万

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部署・役職名 Senior Scientist, Molecular Pathology Group【100年以上の歴史を持つ日系製薬メーカー】
職種
業種
勤務地
仕事内容 1, General information
・Senior Scientist at Molecular Pathology Group to join R&D center for discovery and development.
Based at Shinagawa R&D center you will be at the cutting edge of translational science for the global pharmaceutical company. You will have the influence to impact an industry-leading portfolio of programs from early clinical development of novel therapeutics through drug approval and companion diagnostic development that support approved targeted therapies.
This position is expected to lead molecular pathology group requiring experience in oncology and specialty medicine.
Especially, a person, who is experienced in an antibody-drug conjugate therapy related target expression and drug response analysis from human specimens, is preferable.
The researcher who is experienced and interested in immunohistochemical assay development, communication with global PIs, institutional pathologists and global CROs.

2,Responsibilities
・Deliver biomarkers for clinical studies based on cutting edge science and technologies. Generating disease linkage data to guide indication selection and targeted patient populations.
・Measure target expression to inform clinical decisions for selecting therapeutically relevant indications. You will understand key cancer pathway interactions and feedback mechanisms in clinical samples to guide rational drug combinations.
・Define novel mechanisms of resistance targeted therapies by studying tumors at relapse and delivering multiplex pathology assays using a variety of tissue-based methods.
・Develop IHC assay for project related molecules to evaluate patient selection marker feasibility and PD response marker feasibility toward clinical trial. Histopathological analysis of human samples to contribute on drug efficacy evaluation, toxicological insight and decision making of target indication selection for projects.
・Communication with project team, PIs and CROs globally for IHC assay creation, evaluation, transfer and provide support on troubleshooting to those assays on timely manner.
・Prepare documents and presentation materials of scientific outcomes to project team group, corporate seniors and health authorities on time.
・Leadership on new platform and infrastructure creation on histopathological research environment.
・Leadership on team management of molecular pathology group in translational research.
応募資格

【必須(MUST)】

・M.D. Pathologist.
・Strong knowledge in human pathology and biology in Oncology and Specialty Medicine.
・Strong experience in state of art molecular histopathology (including multi-plexed target detection) and molecular histopathological assay development.
・Experience in IHC assay operation and troubleshooting (if there was any).
・Capability to communicate with internal and external colleagues to lead scientific discussion, assay transfer assay to CROs.
・Experience of team management of division, group or projects.

更新日 2019/11/21
求人番号 1179767

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